Beasley, Allen, Crow, Methvin, Portis & Miles, P.C.

Another Nephrogenic Systemic Fibrosis (NSF) study has tied the debilitating condition to Gadolinium contrast agents used in Magnetic Resonance Imaging (MRI). This latest NSF research was conducted by the Centers for Disease Control (CDC), which examined a cluster of NSF patients at one unidentified St. Louis Missouri Hospital. The CDC found that the exposure to Gadolinium contrast dyes during MRI was independently associated with the development of NSF.

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Gadolinium based MRI contrast agents have been implicated in at least 1,000 cases of a debilitating disorder called Nephrogenic Systemic Fibrosis/ Nephrogenic Fibrosing Dermopathy (NSF/NSD) around the world. This horrible disease causes a buildup of collagen in tissues, leading to a severe thickening and hardening of the skin. NSF/NSD can completely immobilize patients, and in severe cases it can lead to death.

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If she knew then what she knows now, Sarah Fracella would not have undergone an MRI. “I don’t think there’s been a day in the last, probably, two years that’s gone by that I haven’t cried at least once about this,” said Fracella, 38, of Santa Barbara, whose skin is hardening painfully into something that looks startlingly like marble.

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Gadolinium based contrast agents used during MRIs, are known to be associated with the onset of Nephrogenic Systemic Fibrosis/ Nephrogenic Fibrosing Dermopathy (NSF/NSD) in patients with pre-existing kidney disease.

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Gadolinium based MRI contrast agents and Nephrogenic Systemic Fibrosis/ Nephrogenic Fibrosing Dermopathy (NSF/NFD) have been linked in yet another study. This time, researchers in Scotland have confirmed that gadolinium based contrast agents used in MRI’s are strongly associated with the onset of this often fatal disorder in people suffering from pre-existing kidney disease. Their findings only add to the growing body of evidence that shows a strong connection between NSF/NFD and gadolinium based contrast agents that are often used in MRIs.

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The U.S. FDA indicated that it would start adding its strongest ‘black box’ warnings to gadolinium based contrast agents used in MRIs by May of next year.

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Nephrogenic Systemic Fibrosis/ Nephrogenic Fibrosing Dermopathy (NSF/NFD), a painful conditions that has been linked to the use of gadolinium based contrast agents used in Magnetic Resonance Imaging (MRI), could be more prevalent than once thought.

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